Shoc2/Sur8 Protein Regulates Neurite Outgrowth

The Shoc2 protein has been implicated in the positive regulation of the Ras-ERK pathway by increasing the functional binding interaction between Ras and Raf, leading to increased ERK activity. Here we found that Shoc2 overexpression induced sustained ERK phosphorylation, notably in the case of EGF s...

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Detalles Bibliográficos
Autores principales: Leon, Gonzalo, Sanchez-Ruiloba, Lucia, Perez-Rodriguez, Andrea, Gragera, Teresa, Martinez, Natalia, Hernandez, Silvia, Anta, Berta, Calero, Olga, Garcia-Dominguez, Carlota A., Dura, Lara M., Peña-Jimenez, Daniel, Castro, Judit, Zarich, Natasha, Sanchez-Gomez, Pilar, Calero, Miguel, Iglesias, Teresa, Oliva, Jose L., Rojas, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267731/
https://www.ncbi.nlm.nih.gov/pubmed/25514808
http://dx.doi.org/10.1371/journal.pone.0114837

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