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PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema

BACKGROUND: Chronic pulmonary obstructive disease (COPD) has become the fourth leading cause of death worldwide. Cigarette smoking induces neutrophil elastase (NE) and contributes to COPD, but the detailed mechanisms involved are not fully established. In an animal model of pulmonary emphysema, ther...

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Detalles Bibliográficos
Autores principales: Hou, Hsin-Han, Cheng, Shih-Lung, Chung, Kuei-Pin, Wei, Shu-Chen, Tsao, Po-Nien, Lu, Hsuan-Hsuan, Wang, Hao-Chien, Yu, Chong-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267747/
https://www.ncbi.nlm.nih.gov/pubmed/25186164
http://dx.doi.org/10.1186/s12931-014-0106-1

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