Uric Acid Promotes Apoptosis in Human Proximal Tubule Cells by Oxidative Stress and the Activation of NADPH Oxidase NOX 4

Mild hyperuricemia has been linked to the development and progression of tubulointerstitial renal damage. However the mechanisms by which uric acid may cause these effects are poorly explored. We investigated the effect of uric acid on apoptosis and the underlying mechanisms in a human proximal tubu...

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Detalles Bibliográficos
Autores principales: Verzola, Daniela, Ratto, Elena, Villaggio, Barbara, Parodi, Emanuele Luigi, Pontremoli, Roberto, Garibotto, Giacomo, Viazzi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267812/
https://www.ncbi.nlm.nih.gov/pubmed/25514209
http://dx.doi.org/10.1371/journal.pone.0115210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267812/
https://www.ncbi.nlm.nih.gov/pubmed/25514209
http://dx.doi.org/10.1371/journal.pone.0115210

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