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SERPINB3/B4 contributes to early inflammation and barrier dysfunction in an experimental murine model of atopic dermatitis
Serine proteases are critical for epidermal barrier homeostasis and their aberrant expression and/or activity is associated with chronic skin diseases. Elevated levels of the serine protease inhibitors SERPINB3 and SERPINB4 are seen in patients with atopic dermatitis and psoriasis. However their mec...
Autores principales: | Sivaprasad, Umasundari, Kinker, Kayla G., Ericksen, Mark B., Lindsey, Mark, Gibson, Aaron M., Bass, Stacey A., Hershey, Nicolas S., Deng, Jingyuan, Medvedovic, Mario, Khurana Hershey, Gurjit K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268075/ https://www.ncbi.nlm.nih.gov/pubmed/25111616 http://dx.doi.org/10.1038/jid.2014.353 |
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