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Epigenetic mechanisms of tumorigenicity manifesting in stem cells

One of the biggest roadblocks to using stem cells as the basis for regenerative medicine therapies is the tumorigenicity of stem cells. Unfortunately, the unique abilities of stem cells to self-renew and differentiate into a variety of cell types are also mechanistically linked to their tumorigenic...

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Detalles Bibliográficos
Autores principales: Tung, Po-Yuan, Knoepfler, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268091/
https://www.ncbi.nlm.nih.gov/pubmed/24931168
http://dx.doi.org/10.1038/onc.2014.172

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