Cargando…

Adipocyte-Specific IKKβ Signaling Suppresses Adipose Tissue Inflammation through an IL-13-Dependent Paracrine Feedback Pathway

Adipose tissue inflammation is one pathway shown to mediate insulin resistance in obese humans and rodents. Obesity induces dynamic cellular changes in adipose tissue to increase proinflammatory cytokines and diminish anti-inflammatory cytokines. However, we have found that anti-inflammatory interle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kwon, Hyokjoon, Laurent, Sarnia, Tang, Yan, Zong, Haihong, Vemulapalli, Pratibha, Pessin, Jeffrey E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268106/ https://www.ncbi.nlm.nih.gov/pubmed/25466256 http://dx.doi.org/10.1016/j.celrep.2014.10.068

Ejemplares similares

High-Fat Diet–Induced Adipocyte Cell Death Occurs Through a Cyclophilin D Intrinsic Signaling Pathway Independent of Adipose Tissue Inflammation
por: Feng, Daorong, et al.
Publicado: (2011)

Fyn Deficiency Promotes a Preferential Increase in Subcutaneous Adipose Tissue Mass and Decreased Visceral Adipose Tissue Inflammation
por: Lee, Ting-Wen A., et al.
Publicado: (2013)

IKKβ Is Essential for Adipocyte Survival and Adaptive Adipose Remodeling in Obesity
por: Park, Se-Hyung, et al.
Publicado: (2016)

Adipokines Mediate Inflammation and Insulin Resistance
por: Kwon, Hyokjoon, et al.
Publicado: (2013)

Peritumoral adipose tissue promotes lipolysis and white adipocytes browning by paracrine action
por: Pagnotta, Priscila, et al.
Publicado: (2023)

TIGAR deficiency enhances skeletal muscle thermogenesis by increasing neuromuscular junction cholinergic signaling
por: Tang, Yan, et al.
Publicado: (2022)

The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development
por: Picarda, Elodie, et al.
Publicado: (2022)

Beneficial paracrine effects of adipocytes from obese rats on cultured endothelial cells
por: Jenkins, Nathan T., et al.
Publicado: (2014)

A paracrine role for white thermogenic adipocytes in innervation: an evidence-based hypothesis
por: Lee, Aejin, et al.
Publicado: (2019)

Paracrine Interactions between Adipocytes and Tumor Cells Recruit and Modify Macrophages to the Mammary Tumor Microenvironment: The Role of Obesity and Inflammation in Breast Adipose Tissue
por: Santander, Ana M., et al.
Publicado: (2015)

Deficiency of Adipocyte IKKβ Affects Atherosclerotic Plaque Vulnerability in Obese LDLR Deficient Mice
por: Lu, Weiwei, et al.
Publicado: (2019)

The Role of IL-13 and IL-4 in Adipose Tissue Fibrosis
por: Arndt, Lilli, et al.
Publicado: (2023)

In vitro analyses of paracrine effects of murine classically activated macrophage on beige adipocyte metabolism
por: Yao, Jingfei, et al.
Publicado: (2022)

Adipocyte-Derived Paracrine Factors Regulate the In Vitro Development of Bovine Mammary Epithelial Cells
por: Dzięgelewska-Sokołowska, Żaneta, et al.
Publicado: (2023)

Inhibition of γ-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation
por: Sparling, David P., et al.
Publicado: (2020)

Ursolic acid induces the production of IL6 and chemokines in both adipocytes and adipose tissue
por: Feng, Bin, et al.
Publicado: (2020)

Euglena extract suppresses adipocyte-differentiation in human adipose-derived stem cells
por: Sugimoto, Ryota, et al.
Publicado: (2018)

The paracrine effects of adipocytes on lipid metabolism in doxorubicin-treated triple negative breast cancer cells
por: Mentoor, Ilze, et al.
Publicado: (2021)

Mapping of R-SNARE function at distinct intracellular GLUT4 trafficking steps in adipocytes
por: Williams, Dumaine, et al.
Publicado: (2008)

Paracrine Effects of Adipose-Derived Stem Cells on Keratinocytes and Dermal Fibroblasts
por: Lee, Seung Ho, et al.
Publicado: (2012)

The paracrine effect of adipose-derived stem cells inhibits osteoarthritis progression
por: Kuroda, Kazunari, et al.
Publicado: (2015)

A TRAIL-TL1A Paracrine Network Involving Adipocytes, Macrophages, and Lymphocytes Induces Adipose Tissue Dysfunction Downstream of E2F1 in Human Obesity
por: Maixner, Nitzan, et al.
Publicado: (2020)

Paracrine IL-33 Stimulation Enhances Lipopolysaccharide-Mediated Macrophage Activation
por: Ohno, Tatsukuni, et al.
Publicado: (2011)

Apigenin blocks IKKα activation and suppresses prostate cancer progression
por: Shukla, Sanjeev, et al.
Publicado: (2015)

Identification of Atypical Peri-Nuclear Multivesicular Bodies in Oxidative and Glycolytic Skeletal Muscle of Aged and Pompe's Disease Mouse Models
por: Neel, Brian A., et al.
Publicado: (2015)

IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes
por: Zhou, Hao, et al.
Publicado: (2020)

Roles for the IKK-Related Kinases TBK1 and IKKε in Cancer
por: Durand, Joel K., et al.
Publicado: (2018)

Paracrine activity of adipose derived stem cells on limbal epithelial stem cells
por: Sikora, Bartosz, et al.
Publicado: (2021)

Microstructured Polymeric Fabrics Modulating the Paracrine Activity of Adipose-Derived Stem Cells
por: Grilli, Federica, et al.
Publicado: (2023)

Crosstalk between Immune Cells and Adipocytes Requires Both Paracrine Factors and Cell Contact to Modify Cytokine Secretion
por: Nitta, Carolina Franco, et al.
Publicado: (2013)

7,8-Dihydroxyflavone Attenuates Inflammatory Response and Insulin Resistance Induced by the Paracrine Interaction between Adipocytes and Macrophages
por: Shin, Ye-Eun, et al.
Publicado: (2023)

CHEK2 represses breast stromal fibroblasts and their paracrine tumor-promoting effects through suppressing SDF-1 and IL-6
por: Al-Rakan, Maha A., et al.
Publicado: (2016)

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ
por: Jin, S, et al.
Publicado: (2013)

Activin receptor ALK4 promotes adipose tissue hyperplasia by suppressing differentiation of adipocyte precursors
por: Lee, Ee-Soo, et al.
Publicado: (2022)

Skyldig! - Ikke skyldig! /
por: Coppee, François, 1842-1908. [from old catalog]
Publicado: (1898)

The Mediator complex kinase module is necessary for fructose regulation of liver glycogen levels through induction of glucose-6-phosphatase catalytic subunit (G6pc)
por: Youn, Dou Yeon, et al.
Publicado: (2021)

Metabolic heterogeneity of activated beige/brite adipocytes in inguinal adipose tissue
por: Lee, Yun-Hee, et al.
Publicado: (2017)

IKKα and IKKβ Regulation of DNA Damage-Induced Cleavage of Huntingtin
por: Khoshnan, Ali, et al.
Publicado: (2009)

Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases
por: Olivotto, Eleonora, et al.
Publicado: (2021)

Adipocyte-specific expression of C-type natriuretic peptide suppresses lipid metabolism and adipocyte hypertrophy in adipose tissues in mice fed high-fat diet
por: Bae, Cho-Rong, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_psr3520nq5okd1m7n9aa1qg8lf