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Type I interferons induce lung protease responses following respiratory syncytial virus infection via RIG-I-like receptors

The role of proteases in viral infection of the lung is poorly understood. Thus, we examined MMP and cathepsin proteases in respiratory syncytial virus (RSV) infected mouse lungs. RSV induced gene expression for matrix metalloproteinases (MMP) -2, -3, -7, -8, -9, -10, -12, -13, -14, -16, -17, -19, -...

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Detalles Bibliográficos
Autores principales: Foronjy, Robert F., Taggart, Clifford C., Dabo, Abdoulaye J., Weldon, Sinéad, Cummins, Neville, Geraghty, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268269/
https://www.ncbi.nlm.nih.gov/pubmed/25005357
http://dx.doi.org/10.1038/mi.2014.54