Cardioprotective Effects of Ghrelin in Heart Failure: From Gut to Heart

Chronic heart failure (CHF) is a major cause of morbidity and mortality. Cardioprotective effects of ghrelin, especially in its acylated form have been demonstrated in heart failure (HF) models and exploratory human clinical studies. Hence, it has been proposed for the treatment of HF. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Khatib, Mahalaqua Nazli, Simkhada, Padam, Gode, Dilip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268614/
https://www.ncbi.nlm.nih.gov/pubmed/25538820
http://dx.doi.org/10.4103/1995-705X.144792
_version_ 1782349258492477440
author Khatib, Mahalaqua Nazli
Simkhada, Padam
Gode, Dilip
author_facet Khatib, Mahalaqua Nazli
Simkhada, Padam
Gode, Dilip
author_sort Khatib, Mahalaqua Nazli
collection PubMed
description Chronic heart failure (CHF) is a major cause of morbidity and mortality. Cardioprotective effects of ghrelin, especially in its acylated form have been demonstrated in heart failure (HF) models and exploratory human clinical studies. Hence, it has been proposed for the treatment of HF. However, the underlying mechanism of its protective effects against HF remains unclear. Future researches are needed to evaluate the efficacy of Ghrelin as a new biomarker and prognostic tool and for exploring its therapeutic potential in patients suffering from CHF.
format Online
Article
Text
id pubmed-4268614
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-42686142014-12-23 Cardioprotective Effects of Ghrelin in Heart Failure: From Gut to Heart Khatib, Mahalaqua Nazli Simkhada, Padam Gode, Dilip Heart Views Review Article Chronic heart failure (CHF) is a major cause of morbidity and mortality. Cardioprotective effects of ghrelin, especially in its acylated form have been demonstrated in heart failure (HF) models and exploratory human clinical studies. Hence, it has been proposed for the treatment of HF. However, the underlying mechanism of its protective effects against HF remains unclear. Future researches are needed to evaluate the efficacy of Ghrelin as a new biomarker and prognostic tool and for exploring its therapeutic potential in patients suffering from CHF. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4268614/ /pubmed/25538820 http://dx.doi.org/10.4103/1995-705X.144792 Text en Copyright: © Heart Views http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Khatib, Mahalaqua Nazli
Simkhada, Padam
Gode, Dilip
Cardioprotective Effects of Ghrelin in Heart Failure: From Gut to Heart
title Cardioprotective Effects of Ghrelin in Heart Failure: From Gut to Heart
title_full Cardioprotective Effects of Ghrelin in Heart Failure: From Gut to Heart
title_fullStr Cardioprotective Effects of Ghrelin in Heart Failure: From Gut to Heart
title_full_unstemmed Cardioprotective Effects of Ghrelin in Heart Failure: From Gut to Heart
title_short Cardioprotective Effects of Ghrelin in Heart Failure: From Gut to Heart
title_sort cardioprotective effects of ghrelin in heart failure: from gut to heart
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268614/
https://www.ncbi.nlm.nih.gov/pubmed/25538820
http://dx.doi.org/10.4103/1995-705X.144792
work_keys_str_mv AT khatibmahalaquanazli cardioprotectiveeffectsofghrelininheartfailurefromguttoheart
AT simkhadapadam cardioprotectiveeffectsofghrelininheartfailurefromguttoheart
AT godedilip cardioprotectiveeffectsofghrelininheartfailurefromguttoheart

Ejemplares similares