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Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy
CONTEXT: Antimicrobial efficacy of subgingival chlorhexidine (CHX) application using two different vehicles of delivery. AIMS: The aim was to evaluate the efficacy of CHX varnish and gel as an adjunct to scaling and root planing (SRP) in reducing microbial count within moderate to deep periodontal p...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268626/ https://www.ncbi.nlm.nih.gov/pubmed/25538468 http://dx.doi.org/10.4103/0976-0105.145775 |
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author | Manthena, Sathish Ramesh, Amitha Srikanth, Adusumilli Ramoji Rao, M. V. Preethi, P. Lakshmi Samatha, Y. Pallavi |
author_facet | Manthena, Sathish Ramesh, Amitha Srikanth, Adusumilli Ramoji Rao, M. V. Preethi, P. Lakshmi Samatha, Y. Pallavi |
author_sort | Manthena, Sathish |
collection | PubMed |
description | CONTEXT: Antimicrobial efficacy of subgingival chlorhexidine (CHX) application using two different vehicles of delivery. AIMS: The aim was to evaluate the efficacy of CHX varnish and gel as an adjunct to scaling and root planing (SRP) in reducing microbial count within moderate to deep periodontal pockets. SETTINGS AND DESIGN: Experimental parallel mouth study. SUBJECTS AND METHODS: A total of 30 subjects between the age groups 25 and 55 years having moderate to severe periodontitis, with pocket depth ≥ 5 mm were selected for the study. The selected patients were randomized into three groups of 10 each. Subjects in Group 1 received SRP followed by subgingival application of CHX varnish, subjects in Group 2 received SRP followed by subgingival application of CHX gel, subjects in Group 3 received SRP alone. Subgingival plaque samples were collected to estimate mean motile and nonmotile microbial counts using dark field microscopy at baseline, 1 week, 1 month, and 3 months. RESULTS: After 3 months, there was statistically significant reduction in nonmotile microbial count in all the three groups. Motile microbial count was significantly reduced in all the three groups till 1 month from baseline. Only subjects in Group 1 who received subgingival CHXvarnish after SRP showed a significant reduction in motile microbial count till 3 months from baseline. CONCLUSIONS: Subgingival application of highly concentrated CHX varnish following SRP is beneficial in reducing microbial count in moderate to deep periodontal pockets. |
format | Online Article Text |
id | pubmed-4268626 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-42686262014-12-23 Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy Manthena, Sathish Ramesh, Amitha Srikanth, Adusumilli Ramoji Rao, M. V. Preethi, P. Lakshmi Samatha, Y. Pallavi J Basic Clin Pharm Original Article CONTEXT: Antimicrobial efficacy of subgingival chlorhexidine (CHX) application using two different vehicles of delivery. AIMS: The aim was to evaluate the efficacy of CHX varnish and gel as an adjunct to scaling and root planing (SRP) in reducing microbial count within moderate to deep periodontal pockets. SETTINGS AND DESIGN: Experimental parallel mouth study. SUBJECTS AND METHODS: A total of 30 subjects between the age groups 25 and 55 years having moderate to severe periodontitis, with pocket depth ≥ 5 mm were selected for the study. The selected patients were randomized into three groups of 10 each. Subjects in Group 1 received SRP followed by subgingival application of CHX varnish, subjects in Group 2 received SRP followed by subgingival application of CHX gel, subjects in Group 3 received SRP alone. Subgingival plaque samples were collected to estimate mean motile and nonmotile microbial counts using dark field microscopy at baseline, 1 week, 1 month, and 3 months. RESULTS: After 3 months, there was statistically significant reduction in nonmotile microbial count in all the three groups. Motile microbial count was significantly reduced in all the three groups till 1 month from baseline. Only subjects in Group 1 who received subgingival CHXvarnish after SRP showed a significant reduction in motile microbial count till 3 months from baseline. CONCLUSIONS: Subgingival application of highly concentrated CHX varnish following SRP is beneficial in reducing microbial count in moderate to deep periodontal pockets. Medknow Publications & Media Pvt Ltd 2014-12 /pmc/articles/PMC4268626/ /pubmed/25538468 http://dx.doi.org/10.4103/0976-0105.145775 Text en Copyright: © Journal of Basic and Clinical Pharmacy http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Manthena, Sathish Ramesh, Amitha Srikanth, Adusumilli Ramoji Rao, M. V. Preethi, P. Lakshmi Samatha, Y. Pallavi Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy |
title | Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy |
title_full | Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy |
title_fullStr | Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy |
title_full_unstemmed | Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy |
title_short | Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy |
title_sort | comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268626/ https://www.ncbi.nlm.nih.gov/pubmed/25538468 http://dx.doi.org/10.4103/0976-0105.145775 |
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