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The dosage of Patz1 modulates reprogramming process
The acquisition of pluripotent cells can be achieved by combined overexpression of transcription factors Oct4, Klf4, Sox2 and c-Myc in somatic cells. This cellular reprogramming process overcomes various barriers to re-activate pluripotency genes and re-acquire the highly dynamic pluripotent chromat...
Autores principales: | Ma, Hui, Ow, Jin Rong, Tan, Bobby Cheng Peow, Goh, Ziyi, Feng, Bo, Loh, Yuin Han, Fedele, Monica, Li, Hu, Wu, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268633/ https://www.ncbi.nlm.nih.gov/pubmed/25515777 http://dx.doi.org/10.1038/srep07519 |
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