Aberrant methylation of the SPARC gene promoter and its clinical implication in gastric cancer

Secreted protein acidic and rich in cysteine (SPARC) gene has been shown to be epigenetically silenced in several cancers. We investigated the loss of expression and promoter methylation of this tumor suppressor gene in gastric cancers and correlated the data with clinicopathological features. We ob...

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Detalles Bibliográficos
Autores principales: Chen, Zi-Yi, Zhang, Jun-Ling, Yao, Hong-Xin, Wang, Peng-Yuan, Zhu, Jing, Wang, Wei, Wang, Xin, Wan, Yuan-Lian, Chen, Shan-Wen, Chen, Guo-Wei, Liu, Yu-Cun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268651/
https://www.ncbi.nlm.nih.gov/pubmed/25516351
http://dx.doi.org/10.1038/srep07035

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