Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions

The type I interferon (IFN) response represents the first line of defence to invading pathogens. Internalized viral ribonucleoproteins (vRNPs) of negative-strand RNA viruses induce an early IFN response by interacting with retinoic acid inducible gene I (RIG-I) and its recruitment to mitochondria. H...

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Detalles Bibliográficos
Autores principales: Liedmann, Swantje, Hrincius, Eike R., Guy, Cliff, Anhlan, Darisuren, Dierkes, Rüdiger, Carter, Robert, Wu, Gang, Staeheli, Peter, Green, Douglas R., Wolff, Thorsten, McCullers, Jonathan A., Ludwig, Stephan, Ehrhardt, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268707/
https://www.ncbi.nlm.nih.gov/pubmed/25487526
http://dx.doi.org/10.1038/ncomms6645

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