Emerging issues in peripheral nerve repair☆

It is today widely acknowledged that nerve repair is now more than a matter of perfect microsurgical reconstruction only and that, to further improve clinical outcome, the involvement of different scientific disciplines is required. This evolving reconstructive/regenerative approach is based on the...

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Detalles Bibliográficos
Autores principales: Geuna, Stefano, Tos, Pierluigi, Battiston, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Special Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268727/
https://www.ncbi.nlm.nih.gov/pubmed/25538748
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.29.004
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author Geuna, Stefano
Tos, Pierluigi
Battiston, Bruno
author_facet Geuna, Stefano
Tos, Pierluigi
Battiston, Bruno
author_sort Geuna, Stefano
collection PubMed
description It is today widely acknowledged that nerve repair is now more than a matter of perfect microsurgical reconstruction only and that, to further improve clinical outcome, the involvement of different scientific disciplines is required. This evolving reconstructive/regenerative approach is based on the interdisciplinary and integrated pillars of tissue engineering such as reconstructive microsurgery, transplantation and biomaterials. In this paper, some of the most promising innovations for the tissue engineering of nerves, emerging from basic science investigation, are critically overviewed with special focus on those approaches that appear today to be more suitable for clinical translation.
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spelling pubmed-42687272014-12-23 Emerging issues in peripheral nerve repair☆ Geuna, Stefano Tos, Pierluigi Battiston, Bruno Neural Regen Res Special Issue It is today widely acknowledged that nerve repair is now more than a matter of perfect microsurgical reconstruction only and that, to further improve clinical outcome, the involvement of different scientific disciplines is required. This evolving reconstructive/regenerative approach is based on the interdisciplinary and integrated pillars of tissue engineering such as reconstructive microsurgery, transplantation and biomaterials. In this paper, some of the most promising innovations for the tissue engineering of nerves, emerging from basic science investigation, are critically overviewed with special focus on those approaches that appear today to be more suitable for clinical translation. Medknow Publications & Media Pvt Ltd 2012-10-15 /pmc/articles/PMC4268727/ /pubmed/25538748 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.29.004 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Issue
Geuna, Stefano
Tos, Pierluigi
Battiston, Bruno
Emerging issues in peripheral nerve repair☆
title Emerging issues in peripheral nerve repair☆
title_full Emerging issues in peripheral nerve repair☆
title_fullStr Emerging issues in peripheral nerve repair☆
title_full_unstemmed Emerging issues in peripheral nerve repair☆
title_short Emerging issues in peripheral nerve repair☆
title_sort emerging issues in peripheral nerve repair☆
topic Special Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268727/
https://www.ncbi.nlm.nih.gov/pubmed/25538748
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.29.004
work_keys_str_mv AT geunastefano emergingissuesinperipheralnerverepair
AT tospierluigi emergingissuesinperipheralnerverepair
AT battistonbruno emergingissuesinperipheralnerverepair

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