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Retinal antigen-specific regulatory T cells protect against spontaneous and induced autoimmunity and require local dendritic cells
BACKGROUND: We previously reported that the peripheral regulatory T cells (pTregs) generated ‘on-demand’ in the retina were crucial to retinal immune privilege, and in vitro analysis of retinal dendritic cells (DC) showed they possessed antigen presenting cell (APC) activity that promoted developmen...
Autores principales: | McPherson, Scott W, Heuss, Neal D, Pierson, Mark J, Gregerson, Dale S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268905/ https://www.ncbi.nlm.nih.gov/pubmed/25498509 http://dx.doi.org/10.1186/s12974-014-0205-4 |
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