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Transient Downregulation of Nanog and Oct4 Induced by DETA/NO Exposure in Mouse Embryonic Stem Cells Leads to Mesodermal/Endodermal Lineage Differentiation

The function of pluripotency genes in differentiation is a matter of investigation. We report here that Nanog and Oct4 are reexpressed in two mouse embryonic stem cell (mESC) lines following exposure to the differentiating agent DETA/NO. Both cell lines express a battery of both endoderm and mesoder...

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Detalles Bibliográficos
Autores principales:	Mora-Castilla, Sergio, Tejedo, Juan R., Tapia-Limonchi, Rafael, Díaz, Irene, Hitos, Ana B., Cahuana, Gladys M., Hmadcha, Abdelkrim, Martín, Franz, Soria, Bernat, Bedoya, Francisco J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269087/ https://www.ncbi.nlm.nih.gov/pubmed/25544848 http://dx.doi.org/10.1155/2014/379678

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