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A Pregnant Woman Who Underwent Laparoscopic Adrenalectomy due to Cushing's Syndrome
Cushing's syndrome (CS) may lead to severe maternal and fetal morbidities and even mortalities in pregnancy. However, pregnancy complicates the diagnosis and treatment of CS. This study describes a 26-year-old pregnant woman admitted with hypertension-induced headache. Hormonal analyses perform...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269281/ https://www.ncbi.nlm.nih.gov/pubmed/25544906 http://dx.doi.org/10.1155/2014/283458 |
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author | Diri, Halit Bayram, Fahri Simsek, Yasin Ozkan, Yusuf Akcan, Alper Karahan, Ibrahim Ileri, Ibrahim Aribas, Sulbiye Koc, Mehmet Sait |
author_facet | Diri, Halit Bayram, Fahri Simsek, Yasin Ozkan, Yusuf Akcan, Alper Karahan, Ibrahim Ileri, Ibrahim Aribas, Sulbiye Koc, Mehmet Sait |
author_sort | Diri, Halit |
collection | PubMed |
description | Cushing's syndrome (CS) may lead to severe maternal and fetal morbidities and even mortalities in pregnancy. However, pregnancy complicates the diagnosis and treatment of CS. This study describes a 26-year-old pregnant woman admitted with hypertension-induced headache. Hormonal analyses performed due to her cushingoid phenotype revealed a diagnosis of adrenocorticotropic hormone- (ACTH-) independent CS. MRI showed a 3.5 cm adenoma in her right adrenal gland. After preoperative metyrapone therapy, she underwent a successful unilateral laparoscopic adrenalectomy at 14-week gestation. Although she had a temporary postoperative adrenal insufficiency, hormonal analyses showed that she has been in remission since delivery. Findings in this patient, as well as those in previous patients, indicate that pregnancy is not an absolute contraindication for laparoscopic adrenalectomy. Rather, such surgery should be considered a safe and efficient treatment method for pregnant women with cortisol-secreting adrenal adenomas. |
format | Online Article Text |
id | pubmed-4269281 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-42692812014-12-28 A Pregnant Woman Who Underwent Laparoscopic Adrenalectomy due to Cushing's Syndrome Diri, Halit Bayram, Fahri Simsek, Yasin Ozkan, Yusuf Akcan, Alper Karahan, Ibrahim Ileri, Ibrahim Aribas, Sulbiye Koc, Mehmet Sait Case Rep Endocrinol Case Report Cushing's syndrome (CS) may lead to severe maternal and fetal morbidities and even mortalities in pregnancy. However, pregnancy complicates the diagnosis and treatment of CS. This study describes a 26-year-old pregnant woman admitted with hypertension-induced headache. Hormonal analyses performed due to her cushingoid phenotype revealed a diagnosis of adrenocorticotropic hormone- (ACTH-) independent CS. MRI showed a 3.5 cm adenoma in her right adrenal gland. After preoperative metyrapone therapy, she underwent a successful unilateral laparoscopic adrenalectomy at 14-week gestation. Although she had a temporary postoperative adrenal insufficiency, hormonal analyses showed that she has been in remission since delivery. Findings in this patient, as well as those in previous patients, indicate that pregnancy is not an absolute contraindication for laparoscopic adrenalectomy. Rather, such surgery should be considered a safe and efficient treatment method for pregnant women with cortisol-secreting adrenal adenomas. Hindawi Publishing Corporation 2014 2014-12-03 /pmc/articles/PMC4269281/ /pubmed/25544906 http://dx.doi.org/10.1155/2014/283458 Text en Copyright © 2014 Halit Diri et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Diri, Halit Bayram, Fahri Simsek, Yasin Ozkan, Yusuf Akcan, Alper Karahan, Ibrahim Ileri, Ibrahim Aribas, Sulbiye Koc, Mehmet Sait A Pregnant Woman Who Underwent Laparoscopic Adrenalectomy due to Cushing's Syndrome |
title | A Pregnant Woman Who Underwent Laparoscopic Adrenalectomy due to Cushing's Syndrome |
title_full | A Pregnant Woman Who Underwent Laparoscopic Adrenalectomy due to Cushing's Syndrome |
title_fullStr | A Pregnant Woman Who Underwent Laparoscopic Adrenalectomy due to Cushing's Syndrome |
title_full_unstemmed | A Pregnant Woman Who Underwent Laparoscopic Adrenalectomy due to Cushing's Syndrome |
title_short | A Pregnant Woman Who Underwent Laparoscopic Adrenalectomy due to Cushing's Syndrome |
title_sort | pregnant woman who underwent laparoscopic adrenalectomy due to cushing's syndrome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269281/ https://www.ncbi.nlm.nih.gov/pubmed/25544906 http://dx.doi.org/10.1155/2014/283458 |
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