Detection of Corynebacterium bovis infection in athymic nude mice from a research animal facility in Korea

Corynebacterium (C.) bovis infection in nude mice causes hyperkeratosis and weight loss and has been reported worldwide but not in Korea. In 2011, nude mice from an animal facility in Korea were found to have white flakes on their dorsal skin. Histopathological testing revealed that the mice had hyp...

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Detalles Bibliográficos
Autores principales: Kim, Tae-Hyoun, Kim, Dong-Su, Han, Ju-Hee, Chang, Seo-Na, Kim, Kyung-Sul, Seok, Seung-Hyeok, Kim, Dong-Jae, Park, Jong-Hwan, Park, Jae-Hak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269604/
https://www.ncbi.nlm.nih.gov/pubmed/24962412
http://dx.doi.org/10.4142/jvs.2014.15.4.583
Descripción
Sumario:Corynebacterium (C.) bovis infection in nude mice causes hyperkeratosis and weight loss and has been reported worldwide but not in Korea. In 2011, nude mice from an animal facility in Korea were found to have white flakes on their dorsal skin. Histopathological testing revealed that the mice had hyperkeratosis and Gram-positive bacteria were found in the skin. We identified isolated bacteria from the skin lesions as C. bovis using PCR and 16S rRNA sequencing. To the best of our knowledge, this is the first report of C. bovis infection in nude mice from Korea.

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