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Leishmania braziliensis replication protein A subunit 1: molecular modelling, protein expression and analysis of its affinity for both DNA and RNA

BACKGROUND: Replication factor A (RPA) is a single-strand DNA binding protein involved in DNA replication, recombination and repair processes. It is composed by the subunits RPA-1, RPA-2 and RPA-3; the major DNA-binding activity resides in the subunit 1 of the heterotrimeric RPA complex. In yeast an...

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Detalles Bibliográficos
Autores principales: Nocua, Paola A, Ramirez, Cesar A, Barreto, George E, González, Janneth, Requena, José M, Puerta, Concepción J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269926/
https://www.ncbi.nlm.nih.gov/pubmed/25498946
http://dx.doi.org/10.1186/s13071-014-0573-8

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