Cargando…

Proteomics informed by transcriptomics reveals Hendra virus sensitizes bat cells to TRAIL-mediated apoptosis

BACKGROUND: Bats are a major reservoir of emerging infectious viruses. Many of these viruses are highly pathogenic to humans however bats remain asymptomatic. The mechanism by which bats control viral replication is unknown. Here we utilize an integrated approach of proteomics informed by transcript...

Descripción completa

Detalles Bibliográficos
Autores principales: Wynne, James W, Shiell, Brian J, Marsh, Glenn A, Boyd, Victoria, Harper, Jennifer A, Heesom, Kate, Monaghan, Paul, Zhou, Peng, Payne, Jean, Klein, Reuben, Todd, Shawn, Mok, Lawrence, Green, Diane, Bingham, John, Tachedjian, Mary, Baker, Michelle L, Matthews, David, Wang, Lin-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269970/
https://www.ncbi.nlm.nih.gov/pubmed/25398248
http://dx.doi.org/10.1186/s13059-014-0532-x

Ejemplares similares