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Proteomics informed by transcriptomics reveals Hendra virus sensitizes bat cells to TRAIL-mediated apoptosis
BACKGROUND: Bats are a major reservoir of emerging infectious viruses. Many of these viruses are highly pathogenic to humans however bats remain asymptomatic. The mechanism by which bats control viral replication is unknown. Here we utilize an integrated approach of proteomics informed by transcript...
Autores principales: | Wynne, James W, Shiell, Brian J, Marsh, Glenn A, Boyd, Victoria, Harper, Jennifer A, Heesom, Kate, Monaghan, Paul, Zhou, Peng, Payne, Jean, Klein, Reuben, Todd, Shawn, Mok, Lawrence, Green, Diane, Bingham, John, Tachedjian, Mary, Baker, Michelle L, Matthews, David, Wang, Lin-Fa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269970/ https://www.ncbi.nlm.nih.gov/pubmed/25398248 http://dx.doi.org/10.1186/s13059-014-0532-x |
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