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Lipid raft-based membrane order is important for antigen-specific clonal expansion of CD4(+) T lymphocytes
BACKGROUND: Lipid rafts are cholesterol and saturated lipid-rich, nanometer sized membrane domains that are hypothesized to play an important role in compartmentalization and spatiotemporal regulation of cellular signaling. Lipid rafts contribute to the plasma membrane order and to its spatial asymm...
Autores principales: | Schieffer, Daniel, Naware, Sanya, Bakun, Walter, Bamezai, Anil K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270042/ https://www.ncbi.nlm.nih.gov/pubmed/25494999 http://dx.doi.org/10.1186/s12865-014-0058-8 |
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