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Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4
Lrp4, the muscle receptor for neuronal Agrin, is expressed in the hippocampus and areas involved in cognition. The function of Lrp4 in the brain, however, is unknown, as Lrp4(−/−) mice fail to form neuromuscular synapses and die at birth. Lrp4(−/−) mice, rescued for Lrp4 expression selectively in mu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270049/ https://www.ncbi.nlm.nih.gov/pubmed/25407677 http://dx.doi.org/10.7554/eLife.04287 |