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Differential expression of sirtuin family members in the developing, adult, and aged rat brain
The sirtuins are NAD(+)-dependent protein deacetylases and/or ADP-ribosyltransferases that play roles in metabolic homeostasis, stress response and potentially aging. This enzyme family resides in different subcellular compartments, and acts on a number of different targets in the nucleus, cytoplasm...
Autores principales: | Sidorova-Darmos, Elena, Wither, Robert G., Shulyakova, Natalya, Fisher, Carl, Ratnam, Melanie, Aarts, Michelle, Lilge, Lothar, Monnier, Philippe P., Eubanks, James H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270178/ https://www.ncbi.nlm.nih.gov/pubmed/25566066 http://dx.doi.org/10.3389/fnagi.2014.00333 |
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