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Pre-clinical and Clinical Safety Studies of CMX-2043: A Cytoprotective Lipoic Acid Analogue for Ischaemia–Reperfusion Injury

CMX-2043 is an α-lipoic acid analogue targeted to reduction of cellular injury and organ damage due to ischaemia–reperfusion injury (IRI). It has been shown to be effective in a rat model of cardiac IRI. The studies here reported evaluate its safety and pharmacokinetic profile in preparation for hum...

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Detalles Bibliográficos
Autores principales:	Kates, Steven A, Lader, Alan S, Casale, Ralph, Beeuwkes, Reinier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270215/ https://www.ncbi.nlm.nih.gov/pubmed/24751172 http://dx.doi.org/10.1111/bcpt.12254

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