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Intracellular ATP does not inhibit Slo2.1 K(+) channels

Under normal physiological conditions, the open probability of Slo2.1 K(+) channels is low. Elevation of cytosolic [Na(+)] and [Cl(−)] caused by ischemia or rapid electrical pacing of cells increases the open probability of Slo2.1 channels and the resulting outward current can stabilize the resting...

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Detalles Bibliográficos
Autores principales: Garg, Priyanka, Sanguinetti, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270230/
https://www.ncbi.nlm.nih.gov/pubmed/25214519
http://dx.doi.org/10.14814/phy2.12118