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Epigenetic Function of Activation-Induced Cytidine Deaminase and Its Link to Lymphomagenesis

Activation-induced cytidine deaminase (AID) is essential for somatic hypermutation and class switch recombination of immunoglobulin (Ig) genes during B cell maturation and immune response. Expression of AID is tightly regulated due to its mutagenic and recombinogenic potential, which is known to tar...

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Detalles Bibliográficos
Autores principales:	Dominguez, Pilar M., Shaknovich, Rita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270259/ https://www.ncbi.nlm.nih.gov/pubmed/25566255 http://dx.doi.org/10.3389/fimmu.2014.00642

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