Cargando…
Identification of tetrahydrocarbazoles as novel multifactorial drug candidates for treatment of Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative brain disorder and the most frequent cause of dementia. To date, there are only a few approved drugs for AD, which show little or no effect on disease progression. Impaired intracellular calcium homeostasis is believed to occur early i...
Autores principales: | Honarnejad, K, Daschner, A, Gehring, A P, Szybinska, A, Giese, A, Kuznicki, J, Bracher, F, Herms, J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270312/ https://www.ncbi.nlm.nih.gov/pubmed/25514752 http://dx.doi.org/10.1038/tp.2014.132 |
Ejemplares similares
-
Development and Implementation of a High-Throughput Compound Screening Assay for Targeting Disrupted ER Calcium Homeostasis in Alzheimer's Disease
por: Honarnejad, Kamran, et al.
Publicado: (2013) -
Rhodium(iii) catalyzed olefination and deuteration of tetrahydrocarbazole
por: Peng, Wan, et al.
Publicado: (2021) -
Tetrahydrocarbazoles are a novel class of potent P-type ATPase inhibitors with antifungal activity
por: Bublitz, Maike, et al.
Publicado: (2018) -
Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease
por: Honarnejad, Kamran, et al.
Publicado: (2013) -
Total Synthesis of Bioactive Canthine Alkaloid Cordatanine
Comprising in Situ Double Oxidative Aromatization of Tetrahydrocarbazole
por: Shelar, Santosh V., et al.
Publicado: (2017)