Cargando…

Protective effect of carboxymethylated chitosan on hydrogen peroxide-induced apoptosis in nucleus pulposus cells

Although the etiology of intervertebral disc degeneration is poorly understood, one approach to prevent this process may be to inhibit apoptosis. In the current study, the anti-apoptotic effects of carboxymethylated chitosan (CMCS) in nucleus pulposus (NP) cells were investigated with the aim to enh...

Descripción completa

Detalles Bibliográficos
Autores principales:	HE, BIN, TAO, HAIYING, LIU, SHIQING, WEI, AILIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270326/ https://www.ncbi.nlm.nih.gov/pubmed/25394560 http://dx.doi.org/10.3892/mmr.2014.2942

Ejemplares similares

Hydrogen peroxide induces nucleus pulposus cell apoptosis by ATF4/CHOP signaling pathway
por: Liu, Yi
Publicado: (2020)

Myricetin alleviated hydrogen peroxide-induced cellular senescence of nucleus pulposus cell through regulating SERPINE1
por: Chen, Rongsheng, et al.
Publicado: (2023)

Mitochondrial dependent pathway is involved in the protective effects of carboxymethylated chitosan on nitric oxide-induced apoptosis in chondrocytes
por: He, Bin, et al.
Publicado: (2020)

Hydrogen sulfide is expressed in the human and the rat cultured nucleus pulposus cells and suppresses apoptosis induced by hypoxia
por: Sun, Haolin, et al.
Publicado: (2018)

Protective effects of resveratrol on autologous nucleus pulposus model of radiculopathy
por: Lin, Bin, et al.
Publicado: (2016)

Resveratrol protects against sodium nitroprusside induced nucleus pulposus cell apoptosis by scavenging ROS
por: Li, Kang, et al.
Publicado: (2018)

Inducing Angiogenesis in the Nucleus Pulposus
por: Damle, Sheela R., et al.
Publicado: (2023)

Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells
por: Lian, Chengjie, et al.
Publicado: (2017)

SIRT1 protects against apoptosis by promoting autophagy in degenerative human disc nucleus pulposus cells
por: Jiang, Wei, et al.
Publicado: (2014)

Protective role of 17β-estradiol on tumor necrosis factor-α-induced apoptosis in human nucleus pulposus cells
por: Liu, Huan, et al.
Publicado: (2017)

Hydrogen sulfide regulates autophagy in nucleus pulposus cells under hypoxia
por: Yue, Lei, et al.
Publicado: (2021)

Mesenchymal Stem Cells Protect Nucleus Pulposus Cells from Compression-Induced Apoptosis by Inhibiting the Mitochondrial Pathway
por: Chen, Sheng, et al.
Publicado: (2017)

Pharmacological inhibition of mTORC1 activity protects against inflammation-induced apoptosis of nucleus pulposus cells
por: Chen, Rigao, et al.
Publicado: (2021)

Exercise-induced FNDC5/irisin protects nucleus pulposus cells against senescence and apoptosis by activating autophagy
por: Zhou, Wenxian, et al.
Publicado: (2022)

Spermidine promotes nucleus pulposus autophagy as a protective mechanism against apoptosis and ameliorates disc degeneration
por: Zheng, Zengming, et al.
Publicado: (2018)

Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo
por: Chen, Deheng, et al.
Publicado: (2016)

Plasma Depolymerization of Chitosan in the Presence of Hydrogen Peroxide
por: Ma, Fengming, et al.
Publicado: (2012)

Tauroursodeoxycholic Acid Protects Nucleus Pulposus Cells from Compression-Induced Apoptosis and Necroptosis via Inhibiting Endoplasmic Reticulum Stress
por: Wang, Wenzheng, et al.
Publicado: (2018)

Cycloastragenol and Astragaloside IV activate telomerase and protect nucleus pulposus cells against high glucose-induced senescence and apoptosis
por: Hong, Haofeng, et al.
Publicado: (2021)

Protective Effects of Peroxiredoxin on Hydrogen Peroxide Induced Oxidative Stress and Apoptosis in Cardiomyocytes
por: Park, Keon-Jae, et al.
Publicado: (2012)

Pioglitazone Protects Compression-Mediated Apoptosis in Nucleus Pulposus Mesenchymal Stem Cells by Suppressing Oxidative Stress
por: Hu, Yiqiang, et al.
Publicado: (2019)

Shikonin protects against lipopolysaccharide‐induced inflammation and apoptosis in human nucleus pulposus cells through the nuclear factor‐kappa B pathway
por: Liu, Yuanbin, et al.
Publicado: (2021)

Hypoxia Helps Maintain Nucleus Pulposus Homeostasis by Balancing Autophagy and Apoptosis
por: Kim, Han-Jun, et al.
Publicado: (2020)

Survivin is expressed in degenerated nucleus pulposus cells and is involved in proliferation and the prevention of apoptosis in vitro
por: LIN, YAZHOU, et al.
Publicado: (2016)

The protective effects of dezocine on interleukin-1β-induced inflammation, oxidative stress and apoptosis of human nucleus pulposus cells and the possible mechanisms
por: Zhu, Fang, et al.
Publicado: (2022)

High Substitution Synthesis of Carboxymethyl Chitosan for Properties Improvement of Carboxymethyl Chitosan Films Depending on Particle Sizes
por: Thanakkasaranee, Sarinthip, et al.
Publicado: (2021)

Anemonin reduces hydrogen peroxide-induced oxidative stress, inflammation and extracellular matrix degradation in nucleus pulposus cells by regulating NOX4/NF-κB signaling pathway
por: Ma, Zhijia, et al.
Publicado: (2023)

Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence
por: Li, Xiao-Chuan, et al.
Publicado: (2018)

Gene expression profile of lipopolysaccharide-induced apoptosis of nucleus pulposus cells reversed by syringic acid
por: Zhang, Heng, et al.
Publicado: (2020)

PHARMACOLOGIC TREATMENT OF HYPERALGESIA EXPERIMENTALLY INDUCED BY NUCLEUS PULPOSUS
por: de Souza Grava, André Luiz, et al.
Publicado: (2015)

Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration
por: Erwin, W Mark, et al.
Publicado: (2011)

miR-222 induces apoptosis in human intervertebral disc nucleus pulposus cells by targeting Bcl-2
por: Wang, Wei, et al.
Publicado: (2019)

Taurine attenuates ER stress-associated apoptosis and catabolism in nucleus pulposus cells
por: Yang, Liuxie, et al.
Publicado: (2022)

Determination and comparison of specifics of nucleus pulposus cells of human intervertebral disc in alginate and chitosan–gelatin scaffolds
por: Renani, Hamid Bahramian, et al.
Publicado: (2012)

Modeling and optimization of degree of folate grafted on chitosan and carboxymethyl-chitosan
por: Esfandiarpour-Boroujeni, S., et al.
Publicado: (2015)

Inhibiting Heat Shock Protein 90 Protects Nucleus Pulposus-Derived Stem/Progenitor Cells From Compression-Induced Necroptosis and Apoptosis
por: Hu, Binwu, et al.
Publicado: (2020)

Nutritional deficiency induces nucleus pulposus cell apoptosis via the ATF4-PKM2-AKT signal axis
por: Zhou, Ningfeng, et al.
Publicado: (2022)

IL-1β induces apoptosis and autophagy via mitochondria pathway in human degenerative nucleus pulposus cells
por: Shen, Jieliang, et al.
Publicado: (2017)

MiR-502 Suppresses TNF-α-Induced Nucleus Pulposus Cell Apoptosis by Targeting TARF2
por: Guo, Zhao, et al.
Publicado: (2021)

Hypoglycemic Properties of Oxovanadium (IV) Coordination Compounds with Carboxymethyl-Carrageenan and Carboxymethyl-Chitosan in Alloxan-Induced Diabetic Mice
por: Zhang, Hongyu, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_11eb86h8oesr0bsn9lthjakcqp