Inhibition of poly (ADP-ribose) polymerase and inducible nitric oxide synthase protects against ischemic myocardial damage by reduction of apoptosis

Myocardial infarction (MI) is defined as the deprivation of the myocardial tissue of oxygen and nutrients, resulting in the induction of inflammation and apoptosis of the cardiomyocytes. Poly (ADP-ribose) polymerase 1 (PARP1) is a nuclear enzyme closely associated with MI, that can be activated by D...

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Detalles Bibliográficos
Autores principales: WANG, JUAN, HAO, LIN, WANG, YAN, QIN, WEIDONG, WANG, XIN, ZHAO, TONG, LIU, YUSHENG, SHENG, LIN, DU, YIMENG, ZHANG, MENGYUAN, LU, QINGHUA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270331/
https://www.ncbi.nlm.nih.gov/pubmed/25412407
http://dx.doi.org/10.3892/mmr.2014.2977

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