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Differential NF-κB and MAPK activation underlies fluoride- and TPA-mediated CXCL8 (IL-8) induction in lung epithelial cells
Different toxic agents have a varying potential to induce the production of the proinflammatory chemokine, CXCL8 (interleukin [IL]-8), in lung cells. A critical question is which mechanisms determine the magnitude and persistence of the CXCL8 responses to different stimuli. To approach this, we comp...
Autores principales: | Refsnes, Magne, Skuland, Tonje, Låg, Marit, Schwarze, Per E, Øvrevik, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270361/ https://www.ncbi.nlm.nih.gov/pubmed/25540590 http://dx.doi.org/10.2147/JIR.S69646 |
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