A Synchrotron-Based Hydroxyl Radical Footprinting Analysis of Amyloid Fibrils and Prefibrillar Intermediates with Residue-Specific Resolution

[Image: see text] Structural models of the fibrils formed by the 40-residue amyloid-β (Aβ40) peptide in Alzheimer’s disease typically consist of linear polypeptide segments, oriented approximately perpendicular to the long axis of the fibril, and joined together as parallel in-register β-sheets to f...

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Detalles Bibliográficos
Autores principales: Klinger, Alexandra L., Kiselar, Janna, Ilchenko, Serguei, Komatsu, Hiroaki, Chance, Mark R., Axelsen, Paul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270378/
https://www.ncbi.nlm.nih.gov/pubmed/25382225
http://dx.doi.org/10.1021/bi5010409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270378/
https://www.ncbi.nlm.nih.gov/pubmed/25382225
http://dx.doi.org/10.1021/bi5010409

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