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Activation of Phenylalanine Hydroxylase by Phenylalanine Does Not Require Binding in the Active Site
[Image: see text] Phenylalanine hydroxylase (PheH), a liver enzyme that catalyzes the hydroxylation of excess phenylalanine in the diet to tyrosine, is activated by phenylalanine. The lack of activity at low levels of phenylalanine has been attributed to the N-terminus of the protein’s regulatory do...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270383/ https://www.ncbi.nlm.nih.gov/pubmed/25453233 http://dx.doi.org/10.1021/bi501183x |