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Reprogramming fibroblasts to pluripotency using arginine-terminated polyamidoamine nanoparticles based non-viral gene delivery system

Induced pluripotent stem cells (iPSCs) have attracted keen interest in regenerative medicine. The generation of iPSCs from somatic cells can be achieved by the delivery of defined transcription factor (Oct4, Sox2, Klf4, and c-Myc[OSKM]). However, most instances of iPSC-generation have been achieved...

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Detalles Bibliográficos
Autores principales:	Zhu, Kai, Li, Jun, Lai, Hao, Yang, Cheng, Guo, Changfa, Wang, Chunsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270399/ https://www.ncbi.nlm.nih.gov/pubmed/25540584 http://dx.doi.org/10.2147/IJN.S73961

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