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Visual Detection of Bacterial Pathogens via PNA-Based Padlock Probe Assembly and Isothermal Amplification of DNAzymes

[Image: see text] We have developed a self-reporting isothermal system for visual bacterial pathogen detection with single base resolution. The new DNA diagnostic is based on combination of peptide nucleic acid (PNA) technology, rolling circle amplification (RCA) and DNAzymes. PNAs are used as excee...

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Detalles Bibliográficos
Autores principales: Gomez, Anastasia, Miller, Nancy S., Smolina, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270401/
https://www.ncbi.nlm.nih.gov/pubmed/25415469
http://dx.doi.org/10.1021/ac5018748