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GEN1 from a Thermophilic Fungus Is Functionally Closely Similar to Non-Eukaryotic Junction-Resolving Enzymes

Processing of Holliday junctions is essential in recombination. We have identified the gene for the junction-resolving enzyme GEN1 from the thermophilic fungus Chaetomium thermophilum and expressed the N-terminal 487-amino-acid section. The protein is a nuclease that is highly selective for four-way...

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Detalles Bibliográficos
Autores principales:	Freeman, Alasdair D.J., Liu, Yijin, Déclais, Anne-Cécile, Gartner, Anton, Lilley, David M.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270448/ https://www.ncbi.nlm.nih.gov/pubmed/25315822 http://dx.doi.org/10.1016/j.jmb.2014.10.008

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