Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import

The common non-steroidal anti-inflammatory drug ibuprofen has been associated with a reduced risk of some age-related pathologies. However, a general pro-longevity role for ibuprofen and its mechanistic basis remains unclear. Here we show that ibuprofen increased the lifespan of Saccharomyces cerevi...

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Detalles Bibliográficos
Autores principales: He, Chong, Tsuchiyama, Scott K., Nguyen, Quynh T., Plyusnina, Ekaterina N., Terrill, Samuel R., Sahibzada, Sarah, Patel, Bhumil, Faulkner, Alena R., Shaposhnikov, Mikhail V., Tian, Ruilin, Tsuchiya, Mitsuhiro, Kaeberlein, Matt, Moskalev, Alexey A., Kennedy, Brian K., Polymenis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270464/
https://www.ncbi.nlm.nih.gov/pubmed/25521617
http://dx.doi.org/10.1371/journal.pgen.1004860

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