Golgi-Located NTPDase1 of Leishmania major Is Required for Lipophosphoglycan Elongation and Normal Lesion Development whereas Secreted NTPDase2 Is Dispensable for Virulence

Parasitic protozoa, such as Leishmania species, are thought to express a number of surface and secreted nucleoside triphosphate diphosphohydrolases (NTPDases) which hydrolyze a broad range of nucleoside tri- and diphosphates. However, the functional significance of NTPDases in parasite virulence is...

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Detalles Bibliográficos
Autores principales: Sansom, Fiona M., Ralton, Julie E., Sernee, M. Fleur, Cohen, Alice M., Hooker, David J., Hartland, Elizabeth L., Naderer, Thomas, McConville, Malcolm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270689/
https://www.ncbi.nlm.nih.gov/pubmed/25521752
http://dx.doi.org/10.1371/journal.pntd.0003402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270689/
https://www.ncbi.nlm.nih.gov/pubmed/25521752
http://dx.doi.org/10.1371/journal.pntd.0003402

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