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A Feasibility Study of Fricke Dosimetry as an Absorbed Dose to Water Standard for (192)Ir HDR Sources

High dose rate brachytherapy (HDR) using (192)Ir sources is well accepted as an important treatment option and thus requires an accurate dosimetry standard. However, a dosimetry standard for the direct measurement of the absolute dose to water for this particular source type is currently not availab...

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Detalles Bibliográficos
Autores principales: deAlmeida, Carlos Eduardo, Ochoa, Ricardo, de Lima, Marilene Coelho, David, Mariano Gazineu, Pires, Evandro Jesus, Peixoto, José Guilherme, Salata, Camila, Bernal, Mario Antônio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270754/
https://www.ncbi.nlm.nih.gov/pubmed/25521914
http://dx.doi.org/10.1371/journal.pone.0115155
Descripción
Sumario:High dose rate brachytherapy (HDR) using (192)Ir sources is well accepted as an important treatment option and thus requires an accurate dosimetry standard. However, a dosimetry standard for the direct measurement of the absolute dose to water for this particular source type is currently not available. An improved standard for the absorbed dose to water based on Fricke dosimetry of HDR (192)Ir brachytherapy sources is presented in this study. The main goal of this paper is to demonstrate the potential usefulness of the Fricke dosimetry technique for the standardization of the quantity absorbed dose to water for (192)Ir sources. A molded, double-walled, spherical vessel for water containing the Fricke solution was constructed based on the Fricke system. The authors measured the absorbed dose to water and compared it with the doses calculated using the AAPM TG-43 report. The overall combined uncertainty associated with the measurements using Fricke dosimetry was 1.4% for k = 1, which is better than the uncertainties reported in previous studies. These results are promising; hence, the use of Fricke dosimetry to measure the absorbed dose to water as a standard for HDR (192)Ir may be possible in the future.