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A Feasibility Study of Fricke Dosimetry as an Absorbed Dose to Water Standard for (192)Ir HDR Sources

High dose rate brachytherapy (HDR) using (192)Ir sources is well accepted as an important treatment option and thus requires an accurate dosimetry standard. However, a dosimetry standard for the direct measurement of the absolute dose to water for this particular source type is currently not availab...

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Autores principales: deAlmeida, Carlos Eduardo, Ochoa, Ricardo, de Lima, Marilene Coelho, David, Mariano Gazineu, Pires, Evandro Jesus, Peixoto, José Guilherme, Salata, Camila, Bernal, Mario Antônio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270754/
https://www.ncbi.nlm.nih.gov/pubmed/25521914
http://dx.doi.org/10.1371/journal.pone.0115155
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author deAlmeida, Carlos Eduardo
Ochoa, Ricardo
de Lima, Marilene Coelho
David, Mariano Gazineu
Pires, Evandro Jesus
Peixoto, José Guilherme
Salata, Camila
Bernal, Mario Antônio
author_facet deAlmeida, Carlos Eduardo
Ochoa, Ricardo
de Lima, Marilene Coelho
David, Mariano Gazineu
Pires, Evandro Jesus
Peixoto, José Guilherme
Salata, Camila
Bernal, Mario Antônio
author_sort deAlmeida, Carlos Eduardo
collection PubMed
description High dose rate brachytherapy (HDR) using (192)Ir sources is well accepted as an important treatment option and thus requires an accurate dosimetry standard. However, a dosimetry standard for the direct measurement of the absolute dose to water for this particular source type is currently not available. An improved standard for the absorbed dose to water based on Fricke dosimetry of HDR (192)Ir brachytherapy sources is presented in this study. The main goal of this paper is to demonstrate the potential usefulness of the Fricke dosimetry technique for the standardization of the quantity absorbed dose to water for (192)Ir sources. A molded, double-walled, spherical vessel for water containing the Fricke solution was constructed based on the Fricke system. The authors measured the absorbed dose to water and compared it with the doses calculated using the AAPM TG-43 report. The overall combined uncertainty associated with the measurements using Fricke dosimetry was 1.4% for k = 1, which is better than the uncertainties reported in previous studies. These results are promising; hence, the use of Fricke dosimetry to measure the absorbed dose to water as a standard for HDR (192)Ir may be possible in the future.
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spelling pubmed-42707542014-12-26 A Feasibility Study of Fricke Dosimetry as an Absorbed Dose to Water Standard for (192)Ir HDR Sources deAlmeida, Carlos Eduardo Ochoa, Ricardo de Lima, Marilene Coelho David, Mariano Gazineu Pires, Evandro Jesus Peixoto, José Guilherme Salata, Camila Bernal, Mario Antônio PLoS One Research Article High dose rate brachytherapy (HDR) using (192)Ir sources is well accepted as an important treatment option and thus requires an accurate dosimetry standard. However, a dosimetry standard for the direct measurement of the absolute dose to water for this particular source type is currently not available. An improved standard for the absorbed dose to water based on Fricke dosimetry of HDR (192)Ir brachytherapy sources is presented in this study. The main goal of this paper is to demonstrate the potential usefulness of the Fricke dosimetry technique for the standardization of the quantity absorbed dose to water for (192)Ir sources. A molded, double-walled, spherical vessel for water containing the Fricke solution was constructed based on the Fricke system. The authors measured the absorbed dose to water and compared it with the doses calculated using the AAPM TG-43 report. The overall combined uncertainty associated with the measurements using Fricke dosimetry was 1.4% for k = 1, which is better than the uncertainties reported in previous studies. These results are promising; hence, the use of Fricke dosimetry to measure the absorbed dose to water as a standard for HDR (192)Ir may be possible in the future. Public Library of Science 2014-12-18 /pmc/articles/PMC4270754/ /pubmed/25521914 http://dx.doi.org/10.1371/journal.pone.0115155 Text en © 2014 deAlmeida et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
deAlmeida, Carlos Eduardo
Ochoa, Ricardo
de Lima, Marilene Coelho
David, Mariano Gazineu
Pires, Evandro Jesus
Peixoto, José Guilherme
Salata, Camila
Bernal, Mario Antônio
A Feasibility Study of Fricke Dosimetry as an Absorbed Dose to Water Standard for (192)Ir HDR Sources
title A Feasibility Study of Fricke Dosimetry as an Absorbed Dose to Water Standard for (192)Ir HDR Sources
title_full A Feasibility Study of Fricke Dosimetry as an Absorbed Dose to Water Standard for (192)Ir HDR Sources
title_fullStr A Feasibility Study of Fricke Dosimetry as an Absorbed Dose to Water Standard for (192)Ir HDR Sources
title_full_unstemmed A Feasibility Study of Fricke Dosimetry as an Absorbed Dose to Water Standard for (192)Ir HDR Sources
title_short A Feasibility Study of Fricke Dosimetry as an Absorbed Dose to Water Standard for (192)Ir HDR Sources
title_sort feasibility study of fricke dosimetry as an absorbed dose to water standard for (192)ir hdr sources
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270754/
https://www.ncbi.nlm.nih.gov/pubmed/25521914
http://dx.doi.org/10.1371/journal.pone.0115155
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