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LRAT-specific domain facilitates Vitamin A metabolism by domain swapping in HRASLS

Cellular uptake of vitamin A, production of visual chromophore, and triglyceride homeostasis in adipocytes depend on two representatives of the vertebrate N1pC/P60 protein family, lecithin:retinol acyltransferase (LRAT) and HRAS-like tumor suppressor 3 (HRASLS3). Both proteins function as lipid-meta...

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Detalles Bibliográficos
Autores principales: Golczak, Marcin, Sears, Avery E., Kiser, Philip D., Palczewski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270908/
https://www.ncbi.nlm.nih.gov/pubmed/25383759
http://dx.doi.org/10.1038/nchembio.1687