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LRAT-specific domain facilitates Vitamin A metabolism by domain swapping in HRASLS
Cellular uptake of vitamin A, production of visual chromophore, and triglyceride homeostasis in adipocytes depend on two representatives of the vertebrate N1pC/P60 protein family, lecithin:retinol acyltransferase (LRAT) and HRAS-like tumor suppressor 3 (HRASLS3). Both proteins function as lipid-meta...
Autores principales: | Golczak, Marcin, Sears, Avery E., Kiser, Philip D., Palczewski, Krzysztof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270908/ https://www.ncbi.nlm.nih.gov/pubmed/25383759 http://dx.doi.org/10.1038/nchembio.1687 |
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