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Potassium permanganate toxicity: A rare case with difficult airway management and hepatic damage

Potassium permanganate (KMnO(4)) is rarely used for suicidal attempt. Its ingestion can lead to local as well as systemic toxicities due to coagulation necrosis and damage, caused by free radicals of permanganate. We recently managed a case of suicidal ingestion of KMnO(4) in a lethal dose. She had...

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Detalles Bibliográficos
Autores principales: Agrawal, Vijay Kumar, Bansal, Abhishek, Kumar, Ranjeet, Kumawat, Bhanwar Lal, Mahajan, Parul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271282/
https://www.ncbi.nlm.nih.gov/pubmed/25538417
http://dx.doi.org/10.4103/0972-5229.146318
Descripción
Sumario:Potassium permanganate (KMnO(4)) is rarely used for suicidal attempt. Its ingestion can lead to local as well as systemic toxicities due to coagulation necrosis and damage, caused by free radicals of permanganate. We recently managed a case of suicidal ingestion of KMnO(4) in a lethal dose. She had significant narrowing of upper airway leading to difficult intubation as well as hepatic dysfunction and coagulopathy as systemic manifestation. We suggest to keep ourselves ready to handle difficult airway with the aid of fiber optic bronchoscope or surgical airway management in such patients. Upper gastrointestinal (GI) endoscopy should be done at the earliest to determine the extent of upper GI injury and further nutrition planning.