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A Retrospective Study of Marjolin's Ulcer Over an Eleven Year Period

BACKGROUND: Marjolin's ulcer is a rare aggressive cutaneous malignancy occurring in previously occurred wounds. The most common aetiology is a burn wound involving extremities and squamous cell carcinoma is the most common variant. MATERIALS AND METHODS: A retrospective analyses of medical reco...

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Detalles Bibliográficos
Autores principales: Challa, Vasu Reddy, Deshmane, Vijayalakshmi, Ashwatha Reddy, Madhusudana Bommasandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271295/
https://www.ncbi.nlm.nih.gov/pubmed/25538436
http://dx.doi.org/10.4103/0974-2077.146667
Descripción
Sumario:BACKGROUND: Marjolin's ulcer is a rare aggressive cutaneous malignancy occurring in previously occurred wounds. The most common aetiology is a burn wound involving extremities and squamous cell carcinoma is the most common variant. MATERIALS AND METHODS: A retrospective analyses of medical records of patients treated in a single unit with a diagnosis of Marjolin's ulcer was performed. RESULTS: During the study period, 14 patients were treated. Four patients had lymph node metastases and one had pulmonary metastases at the time of presentation. Seven patients underwent wide excision with reconstruction and seven underwent amputation or disarticulation because of advanced malignancy. During the follow up two patients developed local recurrence and one developed pulmonary metastases. Both the patients with pulmonary metastases had Marjolin's ulcer of trunk. CONCLUSION: Marjolin's ulcer occurs more commonly in the extremities. Distant metastases occur commonly in patients with ulcers on the of trunk.