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A Retrospective Study of Marjolin's Ulcer Over an Eleven Year Period

BACKGROUND: Marjolin's ulcer is a rare aggressive cutaneous malignancy occurring in previously occurred wounds. The most common aetiology is a burn wound involving extremities and squamous cell carcinoma is the most common variant. MATERIALS AND METHODS: A retrospective analyses of medical reco...

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Autores principales: Challa, Vasu Reddy, Deshmane, Vijayalakshmi, Ashwatha Reddy, Madhusudana Bommasandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271295/
https://www.ncbi.nlm.nih.gov/pubmed/25538436
http://dx.doi.org/10.4103/0974-2077.146667
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author Challa, Vasu Reddy
Deshmane, Vijayalakshmi
Ashwatha Reddy, Madhusudana Bommasandra
author_facet Challa, Vasu Reddy
Deshmane, Vijayalakshmi
Ashwatha Reddy, Madhusudana Bommasandra
author_sort Challa, Vasu Reddy
collection PubMed
description BACKGROUND: Marjolin's ulcer is a rare aggressive cutaneous malignancy occurring in previously occurred wounds. The most common aetiology is a burn wound involving extremities and squamous cell carcinoma is the most common variant. MATERIALS AND METHODS: A retrospective analyses of medical records of patients treated in a single unit with a diagnosis of Marjolin's ulcer was performed. RESULTS: During the study period, 14 patients were treated. Four patients had lymph node metastases and one had pulmonary metastases at the time of presentation. Seven patients underwent wide excision with reconstruction and seven underwent amputation or disarticulation because of advanced malignancy. During the follow up two patients developed local recurrence and one developed pulmonary metastases. Both the patients with pulmonary metastases had Marjolin's ulcer of trunk. CONCLUSION: Marjolin's ulcer occurs more commonly in the extremities. Distant metastases occur commonly in patients with ulcers on the of trunk.
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spelling pubmed-42712952014-12-23 A Retrospective Study of Marjolin's Ulcer Over an Eleven Year Period Challa, Vasu Reddy Deshmane, Vijayalakshmi Ashwatha Reddy, Madhusudana Bommasandra J Cutan Aesthet Surg Original Article BACKGROUND: Marjolin's ulcer is a rare aggressive cutaneous malignancy occurring in previously occurred wounds. The most common aetiology is a burn wound involving extremities and squamous cell carcinoma is the most common variant. MATERIALS AND METHODS: A retrospective analyses of medical records of patients treated in a single unit with a diagnosis of Marjolin's ulcer was performed. RESULTS: During the study period, 14 patients were treated. Four patients had lymph node metastases and one had pulmonary metastases at the time of presentation. Seven patients underwent wide excision with reconstruction and seven underwent amputation or disarticulation because of advanced malignancy. During the follow up two patients developed local recurrence and one developed pulmonary metastases. Both the patients with pulmonary metastases had Marjolin's ulcer of trunk. CONCLUSION: Marjolin's ulcer occurs more commonly in the extremities. Distant metastases occur commonly in patients with ulcers on the of trunk. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4271295/ /pubmed/25538436 http://dx.doi.org/10.4103/0974-2077.146667 Text en Copyright: © Journal of Cutaneous and Aesthetic Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Challa, Vasu Reddy
Deshmane, Vijayalakshmi
Ashwatha Reddy, Madhusudana Bommasandra
A Retrospective Study of Marjolin's Ulcer Over an Eleven Year Period
title A Retrospective Study of Marjolin's Ulcer Over an Eleven Year Period
title_full A Retrospective Study of Marjolin's Ulcer Over an Eleven Year Period
title_fullStr A Retrospective Study of Marjolin's Ulcer Over an Eleven Year Period
title_full_unstemmed A Retrospective Study of Marjolin's Ulcer Over an Eleven Year Period
title_short A Retrospective Study of Marjolin's Ulcer Over an Eleven Year Period
title_sort retrospective study of marjolin's ulcer over an eleven year period
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271295/
https://www.ncbi.nlm.nih.gov/pubmed/25538436
http://dx.doi.org/10.4103/0974-2077.146667
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