Human post-mortem synapse proteome integrity screening for proteomic studies of postsynaptic complexes

BACKGROUND: Synapses are fundamental components of brain circuits and are disrupted in over 100 neurological and psychiatric diseases. The synapse proteome is physically organized into multiprotein complexes and polygenic mutations converge on postsynaptic complexes in schizophrenia, autism and inte...

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Detalles Bibliográficos
Autores principales: Bayés, Àlex, Collins, Mark O, Galtrey, Clare M, Simonnet, Clémence, Roy, Marcia, Croning, Mike DR, Gou, Gemma, van de Lagemaat, Louie N, Milward, David, Whittle, Ian R, Smith, Colin, Choudhary, Jyoti S, Grant, Seth GN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271336/
https://www.ncbi.nlm.nih.gov/pubmed/25429717
http://dx.doi.org/10.1186/s13041-014-0088-4

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