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Leprosy elimination: A myth busted

BACKGROUND: Leprosy is mainly a chronic infectious disease caused by Mycobacterium leprae. The disease mainly affects the skin, the peripheral nerves, mucosa of the upper respiratory tract and eyes. Though the target of leprosy elimination was achieved at national level in 2006 even then a large pro...

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Autores principales: Yadav, Nidhi, Kar, Sumit, Madke, Bhushan, Dashatwar, Digambar, Singh, Neha, Prasad, Kameshwar, Kesari, Vikash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271377/
https://www.ncbi.nlm.nih.gov/pubmed/25540534
http://dx.doi.org/10.4103/0976-3147.145197
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author Yadav, Nidhi
Kar, Sumit
Madke, Bhushan
Dashatwar, Digambar
Singh, Neha
Prasad, Kameshwar
Kesari, Vikash
author_facet Yadav, Nidhi
Kar, Sumit
Madke, Bhushan
Dashatwar, Digambar
Singh, Neha
Prasad, Kameshwar
Kesari, Vikash
author_sort Yadav, Nidhi
collection PubMed
description BACKGROUND: Leprosy is mainly a chronic infectious disease caused by Mycobacterium leprae. The disease mainly affects the skin, the peripheral nerves, mucosa of the upper respiratory tract and eyes. Though the target of leprosy elimination was achieved at national level in 2006 even then a large proportion of leprosy cases reported globally still constitute from India. AIM AND OBJECTIVE: To study the clinico-epidemiological profile of new cases of leprosy in a rural tertiary hospital. MATERIALS AND METHODS: Thirty-five newly diagnosed cases of leprosy presented in out-patient/admitted in the department of Dermatology, Venereology and Leprosy (between September 2012 and August 2013) were included in the study. Detailed history regarding leprosy, deformity, sensory loss, skin smear for AFB and histopathological examination were done in every patient. RESULTS: The incidence was more in age group of 20 to 39 years (48.57%) and 40 to 59 years (37.14%). 68.57% were males. 48.57% cases were found to have facial deformity and ear lobe thickening was found to be pre-dominant form of facial deformity. Ulnar (88.87%) and common peroneal nerve (34.28%) were the most commonly involved nerves. The split skin smear examination was found to be positive in 27 out of 35 cases. On histopathological examination 10 patients (28.57%) were of lepromatous pole (LL), 4 (11.43%) were of indeterminate, 6 (17.14%) were of tuberculoid type (TT), 4 BT (11.4%) and 1 BL type (2.8%). CONCLUSIONS: This study helps in concluding that leprosy is still not eliminated. Active surveillance is still needed to detect the sub-clinical cases and undiagnosed cases.
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spelling pubmed-42713772014-12-24 Leprosy elimination: A myth busted Yadav, Nidhi Kar, Sumit Madke, Bhushan Dashatwar, Digambar Singh, Neha Prasad, Kameshwar Kesari, Vikash J Neurosci Rural Pract Original Article BACKGROUND: Leprosy is mainly a chronic infectious disease caused by Mycobacterium leprae. The disease mainly affects the skin, the peripheral nerves, mucosa of the upper respiratory tract and eyes. Though the target of leprosy elimination was achieved at national level in 2006 even then a large proportion of leprosy cases reported globally still constitute from India. AIM AND OBJECTIVE: To study the clinico-epidemiological profile of new cases of leprosy in a rural tertiary hospital. MATERIALS AND METHODS: Thirty-five newly diagnosed cases of leprosy presented in out-patient/admitted in the department of Dermatology, Venereology and Leprosy (between September 2012 and August 2013) were included in the study. Detailed history regarding leprosy, deformity, sensory loss, skin smear for AFB and histopathological examination were done in every patient. RESULTS: The incidence was more in age group of 20 to 39 years (48.57%) and 40 to 59 years (37.14%). 68.57% were males. 48.57% cases were found to have facial deformity and ear lobe thickening was found to be pre-dominant form of facial deformity. Ulnar (88.87%) and common peroneal nerve (34.28%) were the most commonly involved nerves. The split skin smear examination was found to be positive in 27 out of 35 cases. On histopathological examination 10 patients (28.57%) were of lepromatous pole (LL), 4 (11.43%) were of indeterminate, 6 (17.14%) were of tuberculoid type (TT), 4 BT (11.4%) and 1 BL type (2.8%). CONCLUSIONS: This study helps in concluding that leprosy is still not eliminated. Active surveillance is still needed to detect the sub-clinical cases and undiagnosed cases. Medknow Publications & Media Pvt Ltd 2014-11 /pmc/articles/PMC4271377/ /pubmed/25540534 http://dx.doi.org/10.4103/0976-3147.145197 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Yadav, Nidhi
Kar, Sumit
Madke, Bhushan
Dashatwar, Digambar
Singh, Neha
Prasad, Kameshwar
Kesari, Vikash
Leprosy elimination: A myth busted
title Leprosy elimination: A myth busted
title_full Leprosy elimination: A myth busted
title_fullStr Leprosy elimination: A myth busted
title_full_unstemmed Leprosy elimination: A myth busted
title_short Leprosy elimination: A myth busted
title_sort leprosy elimination: a myth busted
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271377/
https://www.ncbi.nlm.nih.gov/pubmed/25540534
http://dx.doi.org/10.4103/0976-3147.145197
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