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Leprosy elimination: A myth busted
BACKGROUND: Leprosy is mainly a chronic infectious disease caused by Mycobacterium leprae. The disease mainly affects the skin, the peripheral nerves, mucosa of the upper respiratory tract and eyes. Though the target of leprosy elimination was achieved at national level in 2006 even then a large pro...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271377/ https://www.ncbi.nlm.nih.gov/pubmed/25540534 http://dx.doi.org/10.4103/0976-3147.145197 |
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author | Yadav, Nidhi Kar, Sumit Madke, Bhushan Dashatwar, Digambar Singh, Neha Prasad, Kameshwar Kesari, Vikash |
author_facet | Yadav, Nidhi Kar, Sumit Madke, Bhushan Dashatwar, Digambar Singh, Neha Prasad, Kameshwar Kesari, Vikash |
author_sort | Yadav, Nidhi |
collection | PubMed |
description | BACKGROUND: Leprosy is mainly a chronic infectious disease caused by Mycobacterium leprae. The disease mainly affects the skin, the peripheral nerves, mucosa of the upper respiratory tract and eyes. Though the target of leprosy elimination was achieved at national level in 2006 even then a large proportion of leprosy cases reported globally still constitute from India. AIM AND OBJECTIVE: To study the clinico-epidemiological profile of new cases of leprosy in a rural tertiary hospital. MATERIALS AND METHODS: Thirty-five newly diagnosed cases of leprosy presented in out-patient/admitted in the department of Dermatology, Venereology and Leprosy (between September 2012 and August 2013) were included in the study. Detailed history regarding leprosy, deformity, sensory loss, skin smear for AFB and histopathological examination were done in every patient. RESULTS: The incidence was more in age group of 20 to 39 years (48.57%) and 40 to 59 years (37.14%). 68.57% were males. 48.57% cases were found to have facial deformity and ear lobe thickening was found to be pre-dominant form of facial deformity. Ulnar (88.87%) and common peroneal nerve (34.28%) were the most commonly involved nerves. The split skin smear examination was found to be positive in 27 out of 35 cases. On histopathological examination 10 patients (28.57%) were of lepromatous pole (LL), 4 (11.43%) were of indeterminate, 6 (17.14%) were of tuberculoid type (TT), 4 BT (11.4%) and 1 BL type (2.8%). CONCLUSIONS: This study helps in concluding that leprosy is still not eliminated. Active surveillance is still needed to detect the sub-clinical cases and undiagnosed cases. |
format | Online Article Text |
id | pubmed-4271377 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-42713772014-12-24 Leprosy elimination: A myth busted Yadav, Nidhi Kar, Sumit Madke, Bhushan Dashatwar, Digambar Singh, Neha Prasad, Kameshwar Kesari, Vikash J Neurosci Rural Pract Original Article BACKGROUND: Leprosy is mainly a chronic infectious disease caused by Mycobacterium leprae. The disease mainly affects the skin, the peripheral nerves, mucosa of the upper respiratory tract and eyes. Though the target of leprosy elimination was achieved at national level in 2006 even then a large proportion of leprosy cases reported globally still constitute from India. AIM AND OBJECTIVE: To study the clinico-epidemiological profile of new cases of leprosy in a rural tertiary hospital. MATERIALS AND METHODS: Thirty-five newly diagnosed cases of leprosy presented in out-patient/admitted in the department of Dermatology, Venereology and Leprosy (between September 2012 and August 2013) were included in the study. Detailed history regarding leprosy, deformity, sensory loss, skin smear for AFB and histopathological examination were done in every patient. RESULTS: The incidence was more in age group of 20 to 39 years (48.57%) and 40 to 59 years (37.14%). 68.57% were males. 48.57% cases were found to have facial deformity and ear lobe thickening was found to be pre-dominant form of facial deformity. Ulnar (88.87%) and common peroneal nerve (34.28%) were the most commonly involved nerves. The split skin smear examination was found to be positive in 27 out of 35 cases. On histopathological examination 10 patients (28.57%) were of lepromatous pole (LL), 4 (11.43%) were of indeterminate, 6 (17.14%) were of tuberculoid type (TT), 4 BT (11.4%) and 1 BL type (2.8%). CONCLUSIONS: This study helps in concluding that leprosy is still not eliminated. Active surveillance is still needed to detect the sub-clinical cases and undiagnosed cases. Medknow Publications & Media Pvt Ltd 2014-11 /pmc/articles/PMC4271377/ /pubmed/25540534 http://dx.doi.org/10.4103/0976-3147.145197 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Yadav, Nidhi Kar, Sumit Madke, Bhushan Dashatwar, Digambar Singh, Neha Prasad, Kameshwar Kesari, Vikash Leprosy elimination: A myth busted |
title | Leprosy elimination: A myth busted |
title_full | Leprosy elimination: A myth busted |
title_fullStr | Leprosy elimination: A myth busted |
title_full_unstemmed | Leprosy elimination: A myth busted |
title_short | Leprosy elimination: A myth busted |
title_sort | leprosy elimination: a myth busted |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271377/ https://www.ncbi.nlm.nih.gov/pubmed/25540534 http://dx.doi.org/10.4103/0976-3147.145197 |
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