Baclofen in the short-term maintenance treatment of benzodiazepine dependence

Benzodiazepine (BZD) dependence is a significant public health problem. Apart from the long-term tapering doses of BZD, no others drugs are available for the maintenance treatment of BZD dependence. Baclofen has been used in alcohol and other drug dependence as long-term anti-craving agent. Since al...

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Detalles Bibliográficos
Autores principales: Shukla, Lekhansh, Kandasamy, Arun, Kesavan, Muralidharan, Benegal, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271384/
https://www.ncbi.nlm.nih.gov/pubmed/25540541
http://dx.doi.org/10.4103/0976-3147.145203
Descripción
Sumario:Benzodiazepine (BZD) dependence is a significant public health problem. Apart from the long-term tapering doses of BZD, no others drugs are available for the maintenance treatment of BZD dependence. Baclofen has been used in alcohol and other drug dependence as long-term anti-craving agent. Since alcohol and BZD act through the GABA receptor, we attempted to study the effect of Baclofen as maintenance treatment in a series of five cases with BZD dependence.

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