Baclofen in the short-term maintenance treatment of benzodiazepine dependence

Benzodiazepine (BZD) dependence is a significant public health problem. Apart from the long-term tapering doses of BZD, no others drugs are available for the maintenance treatment of BZD dependence. Baclofen has been used in alcohol and other drug dependence as long-term anti-craving agent. Since al...

Descripción completa

Detalles Bibliográficos
Autores principales: Shukla, Lekhansh, Kandasamy, Arun, Kesavan, Muralidharan, Benegal, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271384/
https://www.ncbi.nlm.nih.gov/pubmed/25540541
http://dx.doi.org/10.4103/0976-3147.145203
_version_ 1782349594491879424
author Shukla, Lekhansh
Kandasamy, Arun
Kesavan, Muralidharan
Benegal, Vivek
author_facet Shukla, Lekhansh
Kandasamy, Arun
Kesavan, Muralidharan
Benegal, Vivek
author_sort Shukla, Lekhansh
collection PubMed
description Benzodiazepine (BZD) dependence is a significant public health problem. Apart from the long-term tapering doses of BZD, no others drugs are available for the maintenance treatment of BZD dependence. Baclofen has been used in alcohol and other drug dependence as long-term anti-craving agent. Since alcohol and BZD act through the GABA receptor, we attempted to study the effect of Baclofen as maintenance treatment in a series of five cases with BZD dependence.
format Online
Article
Text
id pubmed-4271384
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-42713842014-12-24 Baclofen in the short-term maintenance treatment of benzodiazepine dependence Shukla, Lekhansh Kandasamy, Arun Kesavan, Muralidharan Benegal, Vivek J Neurosci Rural Pract Case Report Benzodiazepine (BZD) dependence is a significant public health problem. Apart from the long-term tapering doses of BZD, no others drugs are available for the maintenance treatment of BZD dependence. Baclofen has been used in alcohol and other drug dependence as long-term anti-craving agent. Since alcohol and BZD act through the GABA receptor, we attempted to study the effect of Baclofen as maintenance treatment in a series of five cases with BZD dependence. Medknow Publications & Media Pvt Ltd 2014-11 /pmc/articles/PMC4271384/ /pubmed/25540541 http://dx.doi.org/10.4103/0976-3147.145203 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Shukla, Lekhansh
Kandasamy, Arun
Kesavan, Muralidharan
Benegal, Vivek
Baclofen in the short-term maintenance treatment of benzodiazepine dependence
title Baclofen in the short-term maintenance treatment of benzodiazepine dependence
title_full Baclofen in the short-term maintenance treatment of benzodiazepine dependence
title_fullStr Baclofen in the short-term maintenance treatment of benzodiazepine dependence
title_full_unstemmed Baclofen in the short-term maintenance treatment of benzodiazepine dependence
title_short Baclofen in the short-term maintenance treatment of benzodiazepine dependence
title_sort baclofen in the short-term maintenance treatment of benzodiazepine dependence
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271384/
https://www.ncbi.nlm.nih.gov/pubmed/25540541
http://dx.doi.org/10.4103/0976-3147.145203
work_keys_str_mv AT shuklalekhansh baclofenintheshorttermmaintenancetreatmentofbenzodiazepinedependence
AT kandasamyarun baclofenintheshorttermmaintenancetreatmentofbenzodiazepinedependence
AT kesavanmuralidharan baclofenintheshorttermmaintenancetreatmentofbenzodiazepinedependence
AT benegalvivek baclofenintheshorttermmaintenancetreatmentofbenzodiazepinedependence

Ejemplares similares