Cargando…
Cerebellar ataxia in a young patient: A rare path to lupus
Cerebellar ataxia is a rare manifestation of neuropsychiatric systemic lupus erythematosus (SLE). Development of vasculitic infarcts in the cerebellum is the most plausible reason of this manifestation. We report the case of a patient who presented with characteristic skin rashes of lupus along with...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271393/ https://www.ncbi.nlm.nih.gov/pubmed/25540550 http://dx.doi.org/10.4103/0976-3147.145212 |
_version_ | 1782349596590080000 |
---|---|
author | Ghosh, Kaushik Chatterjee, Atri Ghosh, Susmita Chakraborty, Sisir |
author_facet | Ghosh, Kaushik Chatterjee, Atri Ghosh, Susmita Chakraborty, Sisir |
author_sort | Ghosh, Kaushik |
collection | PubMed |
description | Cerebellar ataxia is a rare manifestation of neuropsychiatric systemic lupus erythematosus (SLE). Development of vasculitic infarcts in the cerebellum is the most plausible reason of this manifestation. We report the case of a patient who presented with characteristic skin rashes of lupus along with cerebellar signs. Imaging of brain in this patient revealed prominent cerebellar atrophy. She was treated with mycophenolate mofetil and oral corticosteroid, and there was no further progression of her neurological signs after the initiation of therapy. In the clinical context of varied presentations of neurolupus, this is one of the rare sightings and our treatment protocol holds promise as first-line therapy in future. |
format | Online Article Text |
id | pubmed-4271393 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-42713932014-12-24 Cerebellar ataxia in a young patient: A rare path to lupus Ghosh, Kaushik Chatterjee, Atri Ghosh, Susmita Chakraborty, Sisir J Neurosci Rural Pract Case Report Cerebellar ataxia is a rare manifestation of neuropsychiatric systemic lupus erythematosus (SLE). Development of vasculitic infarcts in the cerebellum is the most plausible reason of this manifestation. We report the case of a patient who presented with characteristic skin rashes of lupus along with cerebellar signs. Imaging of brain in this patient revealed prominent cerebellar atrophy. She was treated with mycophenolate mofetil and oral corticosteroid, and there was no further progression of her neurological signs after the initiation of therapy. In the clinical context of varied presentations of neurolupus, this is one of the rare sightings and our treatment protocol holds promise as first-line therapy in future. Medknow Publications & Media Pvt Ltd 2014-11 /pmc/articles/PMC4271393/ /pubmed/25540550 http://dx.doi.org/10.4103/0976-3147.145212 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Ghosh, Kaushik Chatterjee, Atri Ghosh, Susmita Chakraborty, Sisir Cerebellar ataxia in a young patient: A rare path to lupus |
title | Cerebellar ataxia in a young patient: A rare path to lupus |
title_full | Cerebellar ataxia in a young patient: A rare path to lupus |
title_fullStr | Cerebellar ataxia in a young patient: A rare path to lupus |
title_full_unstemmed | Cerebellar ataxia in a young patient: A rare path to lupus |
title_short | Cerebellar ataxia in a young patient: A rare path to lupus |
title_sort | cerebellar ataxia in a young patient: a rare path to lupus |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271393/ https://www.ncbi.nlm.nih.gov/pubmed/25540550 http://dx.doi.org/10.4103/0976-3147.145212 |
work_keys_str_mv | AT ghoshkaushik cerebellarataxiainayoungpatientararepathtolupus AT chatterjeeatri cerebellarataxiainayoungpatientararepathtolupus AT ghoshsusmita cerebellarataxiainayoungpatientararepathtolupus AT chakrabortysisir cerebellarataxiainayoungpatientararepathtolupus |