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Cerebellar ataxia in a young patient: A rare path to lupus

Cerebellar ataxia is a rare manifestation of neuropsychiatric systemic lupus erythematosus (SLE). Development of vasculitic infarcts in the cerebellum is the most plausible reason of this manifestation. We report the case of a patient who presented with characteristic skin rashes of lupus along with...

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Autores principales: Ghosh, Kaushik, Chatterjee, Atri, Ghosh, Susmita, Chakraborty, Sisir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271393/
https://www.ncbi.nlm.nih.gov/pubmed/25540550
http://dx.doi.org/10.4103/0976-3147.145212
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author Ghosh, Kaushik
Chatterjee, Atri
Ghosh, Susmita
Chakraborty, Sisir
author_facet Ghosh, Kaushik
Chatterjee, Atri
Ghosh, Susmita
Chakraborty, Sisir
author_sort Ghosh, Kaushik
collection PubMed
description Cerebellar ataxia is a rare manifestation of neuropsychiatric systemic lupus erythematosus (SLE). Development of vasculitic infarcts in the cerebellum is the most plausible reason of this manifestation. We report the case of a patient who presented with characteristic skin rashes of lupus along with cerebellar signs. Imaging of brain in this patient revealed prominent cerebellar atrophy. She was treated with mycophenolate mofetil and oral corticosteroid, and there was no further progression of her neurological signs after the initiation of therapy. In the clinical context of varied presentations of neurolupus, this is one of the rare sightings and our treatment protocol holds promise as first-line therapy in future.
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spelling pubmed-42713932014-12-24 Cerebellar ataxia in a young patient: A rare path to lupus Ghosh, Kaushik Chatterjee, Atri Ghosh, Susmita Chakraborty, Sisir J Neurosci Rural Pract Case Report Cerebellar ataxia is a rare manifestation of neuropsychiatric systemic lupus erythematosus (SLE). Development of vasculitic infarcts in the cerebellum is the most plausible reason of this manifestation. We report the case of a patient who presented with characteristic skin rashes of lupus along with cerebellar signs. Imaging of brain in this patient revealed prominent cerebellar atrophy. She was treated with mycophenolate mofetil and oral corticosteroid, and there was no further progression of her neurological signs after the initiation of therapy. In the clinical context of varied presentations of neurolupus, this is one of the rare sightings and our treatment protocol holds promise as first-line therapy in future. Medknow Publications & Media Pvt Ltd 2014-11 /pmc/articles/PMC4271393/ /pubmed/25540550 http://dx.doi.org/10.4103/0976-3147.145212 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ghosh, Kaushik
Chatterjee, Atri
Ghosh, Susmita
Chakraborty, Sisir
Cerebellar ataxia in a young patient: A rare path to lupus
title Cerebellar ataxia in a young patient: A rare path to lupus
title_full Cerebellar ataxia in a young patient: A rare path to lupus
title_fullStr Cerebellar ataxia in a young patient: A rare path to lupus
title_full_unstemmed Cerebellar ataxia in a young patient: A rare path to lupus
title_short Cerebellar ataxia in a young patient: A rare path to lupus
title_sort cerebellar ataxia in a young patient: a rare path to lupus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271393/
https://www.ncbi.nlm.nih.gov/pubmed/25540550
http://dx.doi.org/10.4103/0976-3147.145212
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