Cargando…

In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T

Object To evaluate the feasibility of mouse spinal cord MR imaging using echo-planar imaging (EPI). Materials and methods Optimized multi-shot spin-echo-EPI sequences were compared to conventional spin-echo (c-SE) at 11.75 T and used for high-spatially resolved acquisitions and relaxation-time measu...

Descripción completa

Detalles Bibliográficos
Autores principales: Callot, Virginie, Duhamel, Guillaume, Cozzone, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271416/
https://www.ncbi.nlm.nih.gov/pubmed/17661098
http://dx.doi.org/10.1007/s10334-007-0079-x
_version_ 1782349602041626624
author Callot, Virginie
Duhamel, Guillaume
Cozzone, Patrick J.
author_facet Callot, Virginie
Duhamel, Guillaume
Cozzone, Patrick J.
author_sort Callot, Virginie
collection PubMed
description Object To evaluate the feasibility of mouse spinal cord MR imaging using echo-planar imaging (EPI). Materials and methods Optimized multi-shot spin-echo-EPI sequences were compared to conventional spin-echo (c-SE) at 11.75 T and used for high-spatially resolved acquisitions and relaxation-time measurements. Results Good quality images were obtained, with clear delineation of gray and white matter. Acquisition-time gain factor was up to 6 (vs. c-SE) and resolution up to 74 × 94 μm(2) was achieved. T(1) and T(2) relaxation times were reliably measured. Conclusion High-temporally and spatially resolved mouse spinal cord EPI imaging is feasible. This technique should greatly benefit to long acquisition-time experiments (diffusion imaging) and imaging of rapidly-evolving pathologies.
format Online
Article
Text
id pubmed-4271416
institution National Center for Biotechnology Information
language English
publishDate 2007
publisher Springer-Verlag
record_format MEDLINE/PubMed
spelling pubmed-42714162014-12-22 In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T Callot, Virginie Duhamel, Guillaume Cozzone, Patrick J. MAGMA Short Communication Object To evaluate the feasibility of mouse spinal cord MR imaging using echo-planar imaging (EPI). Materials and methods Optimized multi-shot spin-echo-EPI sequences were compared to conventional spin-echo (c-SE) at 11.75 T and used for high-spatially resolved acquisitions and relaxation-time measurements. Results Good quality images were obtained, with clear delineation of gray and white matter. Acquisition-time gain factor was up to 6 (vs. c-SE) and resolution up to 74 × 94 μm(2) was achieved. T(1) and T(2) relaxation times were reliably measured. Conclusion High-temporally and spatially resolved mouse spinal cord EPI imaging is feasible. This technique should greatly benefit to long acquisition-time experiments (diffusion imaging) and imaging of rapidly-evolving pathologies. Springer-Verlag 2007-07-28 2007 /pmc/articles/PMC4271416/ /pubmed/17661098 http://dx.doi.org/10.1007/s10334-007-0079-x Text en © ESMRMB 2007
spellingShingle Short Communication
Callot, Virginie
Duhamel, Guillaume
Cozzone, Patrick J.
In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T
title In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T
title_full In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T
title_fullStr In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T
title_full_unstemmed In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T
title_short In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T
title_sort in vivo mouse spinal cord imaging using echo-planar imaging at 11.75 t
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271416/
https://www.ncbi.nlm.nih.gov/pubmed/17661098
http://dx.doi.org/10.1007/s10334-007-0079-x
work_keys_str_mv AT callotvirginie invivomousespinalcordimagingusingechoplanarimagingat1175t
AT duhamelguillaume invivomousespinalcordimagingusingechoplanarimagingat1175t
AT cozzonepatrickj invivomousespinalcordimagingusingechoplanarimagingat1175t