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In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T
Object To evaluate the feasibility of mouse spinal cord MR imaging using echo-planar imaging (EPI). Materials and methods Optimized multi-shot spin-echo-EPI sequences were compared to conventional spin-echo (c-SE) at 11.75 T and used for high-spatially resolved acquisitions and relaxation-time measu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271416/ https://www.ncbi.nlm.nih.gov/pubmed/17661098 http://dx.doi.org/10.1007/s10334-007-0079-x |
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author | Callot, Virginie Duhamel, Guillaume Cozzone, Patrick J. |
author_facet | Callot, Virginie Duhamel, Guillaume Cozzone, Patrick J. |
author_sort | Callot, Virginie |
collection | PubMed |
description | Object To evaluate the feasibility of mouse spinal cord MR imaging using echo-planar imaging (EPI). Materials and methods Optimized multi-shot spin-echo-EPI sequences were compared to conventional spin-echo (c-SE) at 11.75 T and used for high-spatially resolved acquisitions and relaxation-time measurements. Results Good quality images were obtained, with clear delineation of gray and white matter. Acquisition-time gain factor was up to 6 (vs. c-SE) and resolution up to 74 × 94 μm(2) was achieved. T(1) and T(2) relaxation times were reliably measured. Conclusion High-temporally and spatially resolved mouse spinal cord EPI imaging is feasible. This technique should greatly benefit to long acquisition-time experiments (diffusion imaging) and imaging of rapidly-evolving pathologies. |
format | Online Article Text |
id | pubmed-4271416 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-42714162014-12-22 In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T Callot, Virginie Duhamel, Guillaume Cozzone, Patrick J. MAGMA Short Communication Object To evaluate the feasibility of mouse spinal cord MR imaging using echo-planar imaging (EPI). Materials and methods Optimized multi-shot spin-echo-EPI sequences were compared to conventional spin-echo (c-SE) at 11.75 T and used for high-spatially resolved acquisitions and relaxation-time measurements. Results Good quality images were obtained, with clear delineation of gray and white matter. Acquisition-time gain factor was up to 6 (vs. c-SE) and resolution up to 74 × 94 μm(2) was achieved. T(1) and T(2) relaxation times were reliably measured. Conclusion High-temporally and spatially resolved mouse spinal cord EPI imaging is feasible. This technique should greatly benefit to long acquisition-time experiments (diffusion imaging) and imaging of rapidly-evolving pathologies. Springer-Verlag 2007-07-28 2007 /pmc/articles/PMC4271416/ /pubmed/17661098 http://dx.doi.org/10.1007/s10334-007-0079-x Text en © ESMRMB 2007 |
spellingShingle | Short Communication Callot, Virginie Duhamel, Guillaume Cozzone, Patrick J. In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T |
title | In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T |
title_full | In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T |
title_fullStr | In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T |
title_full_unstemmed | In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T |
title_short | In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T |
title_sort | in vivo mouse spinal cord imaging using echo-planar imaging at 11.75 t |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271416/ https://www.ncbi.nlm.nih.gov/pubmed/17661098 http://dx.doi.org/10.1007/s10334-007-0079-x |
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