Macrophage Infection via Selective Capture of HIV-1-Infected CD4(+) T Cells

Macrophages contribute to HIV-1 pathogenesis by forming a viral reservoir and mediating neurological disorders. Cell-free HIV-1 infection of macrophages is inefficient, in part due to low plasma membrane expression of viral entry receptors. We find that macrophages selectively capture and engulf HIV...

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Detalles Bibliográficos
Autores principales: Baxter, Amy E., Russell, Rebecca A., Duncan, Christopher J.A., Moore, Michael D., Willberg, Christian B., Pablos, Jose L., Finzi, Andrés, Kaufmann, Daniel E., Ochsenbauer, Christina, Kappes, John C., Groot, Fedde, Sattentau, Quentin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271767/
https://www.ncbi.nlm.nih.gov/pubmed/25467409
http://dx.doi.org/10.1016/j.chom.2014.10.010

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